Published by cahoadmin at July 25, 2017

Patients + Research: Wayne Kristoff

Patients + Research is a platform for patients to discuss their relationship and experience with the research that leads to new cures, cares and treatments.

I was diagnosed in June 2014 with Type 2 diabetes.  It was bothersome but not unexpected as I had been told by my family doctor that I was borderline diabetic for a while. My father was also Type 2 and my paternal grandmother had what was described as a “sugar problem” in the late 40’s and early 50’s.  From what has been discussed in our family, I believe that it would be called Type 2 today. At the time of my diagnosis, I was told that I would be on medication for the rest of my life.

Fast forward to mid-December 2015 and I was watching the news on CTV London when a story appeared on an upcoming Lawson Health Research Institute trial taking place at St. Joseph’s Health Care London to see if they could put Type 2 diabetes into remission for a period of time. I would do anything to make things better for my children and grandchildren and there was the possibility of managing my diabetes in another way. Also, with my background in education, I knew the value of research into finding better ways to do things.

Wayne Kristoff participated in a clinical trial at Lawson Health Research Institute for Type 2 diabetes remission

In early February 2016, I was asked to meet so that information could be gathered, expectations outlined, and generally discuss if the study was appropriate for me. Some of the expectations were that I would meet with a dietician, I would keep track of my weekly activity and steps, I would work at losing a minimum of 5% of my body weight, and I would follow the regimen to the best of my ability. I was quite eager to join the study so another appointment was established where I would have blood taken, have a check-up and be randomized, which was explained to me as whether I would be part of the control group or part of the test group.

At the next appointment, everything went well. For the next month I would have weekly visits to the clinic with telephone checks part way through the week. From late March until May, I would attend the clinic every two weeks with all the paper work completed such as a 3-day meal diary, food survey of things I ate over a year, steps, daily insulin dosage and blood testing. I have to say that the visits were a pleasure as they turned into both cheerleading and counselling.

When I went for the checkup in May, it was the end of the intensive drug therapy and I was told to start decreasing the dosage of insulin. Blood was taken for another A1C test and I was to receive a call when the results were back. I remember well where I was and what I was doing when I received the call on May 16 to tell me that the test was good and to stop all diabetic medication.

Wayne Kristoff participated in a clinical trial at Lawson Health Research Institute for Type 2 diabetes remission
Wayne shared his story at our Healthier, Wealthier, Smarter London Field Trip

Whatever the outcome in the future, I have had much more time drug-free than I ever expected when I was first diagnosed. At the end of the trial, I am still not taking diabetic medication and my family doctor will continue to monitor my progress. I am now aware that there are several options for me if and when I need to take medications again. I also have to say that my quality of life is greatly improved.  I have so much more energy than I had before the trial. Not feeling well almost constantly puts a damper on things that you want to do. In the course of this trial I have met some great people that I know are there to support me.

Research such as this at our hospitals is so important because it advances treatment options for patients. It gives the public a chance to see where money goes rather than just in some lab out of sight.  It puts every day faces on research.

In summing up, I feel very privileged to be part of this trial. I would encourage anyone who sees a trial that is appropriate for them to become involved.  Would I do it again?  In a heartbeat and I will certainly be looking for other ways to stay involved.

Read more about Wayne Kristoff and the REMIT study at Lawson Health Research Institute


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Want to add your voice to the Patients + Research blog series? Email or call Elise Bradt at, 416-205-1469, or direct message or tweet at us on Twitter at @CAHOhospitals.

Read more Patients + Research posts and share your own insights on Twitter with the hashtag #onHWS. To learn more about how health research makes Ontario healthier, wealthier and smarter, visit our impact page, and check out our other blog posts and videos.